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The short answer is no, but we have plans to implement a REST API in a future release of Patch for Windows Servers (PWS).
Theoretically, most of the API will work except the important bits, Scanning and Deploying. The reason is Remoting ignores the console session and starts up a different session. The different session will not be able to find the name pipe. This is a limitation of Microsoft’s WCF. You can configure machine groups, credentials and Patch Groups using Remoting and it should work just fine.